What is NCI H460?

The NCI-H460 cell line was derived by A.F. Gazdar and associates in 1982 from the pleural fluid of a patient with large cell cancer of the lung. Gender Male Karyotype. modal numbr = 57; range = 53 to 65. This is a hypotriploid human cell line.

What is A549 cell line?

A549 cells are lung carcinoma epithelial cells that constitute a cell line. A549 is one of the commonly used cell lines for a wide range of research applications.

What are BEAS 2B cells?

BEAS-2B are epithelial cells isolated from normal human bronchial epithelium derived from autopsies of noncancerous individuals.

Are A549 cells metastatic?

However, there were differences in the number of cells per HPF based on the cell type. Among NSCLC cells, A549 formed the least amount of metastatic lesions (0.9 ± 0.35 cells per HPF), while H1299, a metastatic cell line, formed the maximum number of metastatic lesions (3.6 ± 1.03 cells per HPF).

Is A549 a Nsclc?

At Labcorp we have been using A549 as a model of NSCLC for more than 10 years. We have run numerous studies in the subcutaneous setting with a number of standard agents. Above are some examples of response to paclitaxel (Figure 1) and docetaxel, bevacizumab and the combination (Figure 2).

What are the three types of carcinoma?

Types of Carcinoma: Basal Cell, Squamous Cell, and Adenocarcinoma.

What are calu 3 cells?

Calu-3 is a non-small-cell lung cancer cell line that grows in adherent culture and displays epithelial morphology. These cells have constitutively active ErbB2/Her2 due to amplification of the ERBB2 gene.

What are bronchial epithelial cells?

The primary function of the bronchial epithelium is to act as a defensive barrier aiding the maintenance of normal airway function. Bronchial epithelial cells (BEC) form the interface between the external environment and the internal milieu, making it a major target of inhaled insults.

Are A549 cells HeLa cells?

The protein (F3) exhibited significant cytotoxic activity against lung (A549) and cervical (HeLa) cancer cells in a dose-dependent manner at concentrations ranging from 10 µg to 1000 µg/mL, as revealed by the MTT assay.

What are HuH 7 cells?

HuH-7 (hereafter Huh7) is a permanent cell line established from male hepatoma tissue, which was surgically removed from a 57-year-old Japanese male in 1982 (Nakabayashi et al., 1982). Huh7 and its derivatives have been used as a convenient experimental substitute for primary hepatocytes.

What are calu 1 cells?

Description. Calu-1 is a non-small-cell lung cancer (NSCLC) cell line that grows in adherent culture and displays epithelial morphology. These cells express wildtype LKB1, wildtype EGFR, and mutant K-Ras (G12C).

What is normal bronchial epithelium?

The bronchial wall is lined by pseudostratified ciliated columnar epithelium with goblet cells. Note the normal thin basal lamina.

What type of epithelial cells are in the lungs?

The majority of the respiratory tree, from the nasal cavity to the bronchi, is lined by pseudostratified columnar ciliated epithelium. The bronchioles are lined by simple columnar to the cuboidal epithelium, and the alveoli possess a lining of thin squamous epithelium that allows for gas exchange.

What are HuH-7 5 cells?

The human hepatoma-derived HuH-7 cell line and its derivatives (Huh7. 5 and Huh7. 5.1) have been widely used as a convenient experimental substitute for primary hepatocytes. In particular, these cell lines represent host cells suitable for propagating the hepatitis C virus (HCV) in vitro.