What is NMR Lipo profile test?

The NMR LipoProfile® test is an FDA-cleared blood test that directly measures the amount of LDL circulating in the body. “LDL” is low-density lipoprotein and has long been recognized as a major causal factor in the development of heart disease.

How is LDL calculated?

[1] LDL can be calculated by FF (total cholesterol (TC) minus high-density lipoprotein (HDL)-cholesterol minus triglycerides (TGs)/5 in mg/dl) or measured directly in the laboratory.

What is lipoprotein fractionation?

A lipoprotein fractionation test is used to measure your LDL, or “bad cholesterol,” levels.

What are LDL subfractions?

Low density lipoprotein particle number (LDL-P) and individual subfractions ranging in size from very-small to large were associated with CVD (continuous p value (pcont) < 0.001) while adjusting for age, sex, hypertension, smoking, and diabetes.

How do you read lipoprotein results?

Low-density lipoprotein is bad cholesterol. Think of the “L” in LDL as “lousy.” High LDL levels increase the risk of heart disease….Low-density lipoprotein (LDL)

  1. Optimal: Less than 100 mg/dL.
  2. Near optimal: 100-129 mg/dL.
  3. Borderline high: 130-159 mg/dL.
  4. High: 160-189 mg/dL.

What is a good LDL to HDL ratio?

In general: The higher the ratio, the higher the risk. Most healthcare providers want the ratio to be below 5:1. A ratio below 3.5:1 is considered very good.

What is a good small LDL particle number?

Ideally, LDL cholesterol levels should be less than 100 mg/dl. Doctors may not express concern about levels of 100–129 mg/dl for people with no health issues, but they may suggest treatment at this stage for people with heart disease or its risk factors.

What is a good LDL particle size?

All people have LDL that is in a range of sizes that correspond to specific densities (8, 14). The size of the predominant LDL particles determines the classification: 22–25.5 nm is small, 25.6–26.5 nm intermediate, and 26.6–28.5 large (13, 14).

Should LDL particles be large or small?

Smaller, more tightly packed LDL has an easier time getting into arteries. Larger, fluffier particles may be less dangerous. Also, research suggests that a key protein on LDL called apolipoprotein B (apoB) is an important contributor for heart disease risk.

What is a good HDL P level?

The optimal reading for HDL levels is of 60 mg/dL or higher. A reading of less than 40 mg/dL can be a major risk factor for heart disease. A reading from 41 mg/dL to 59 mg/dL is borderline low.

What is a good LDL-P number?

Reference Range for LDL-P LDL-P is measured by a nuclear magnetic resonance (NMR) lipid profile test. A value of less than 1,000 is considered ideal. Above 2,000 is considered very high.

What is a good lipoprotein level?

Most people have Lp(a) levels in the range of under 5 to 29 milligrams per deciliter (mg/dL), which roughly equals under 13 to 73 nanomoles per liter (nmol/L. See item 8 below).

What is more important LDL HDL or triglycerides?

Remember the triglyceride to HDL ratio is the stronger predictor of heart disease, much more so than “just” high cholesterol and LDL/HDL ratios.

How do you read a lipid profile report?

In general, HDL levels of 60 mg/dL or higher are considered to be good. Likewise, levels below 40 mg/dL are considered a risk factor for heart disease….Low-density lipoprotein (LDL)

  1. Optimal: Less than 100 mg/dL.
  2. Near optimal: 100-129 mg/dL.
  3. Borderline high: 130-159 mg/dL.
  4. High: 160-189 mg/dL.

Does size of LDL particles matter?

It turns out that LDL particles are not all created equal. Smaller, more tightly packed LDL has an easier time getting into arteries. Larger, fluffier particles may be less dangerous. Also, research suggests that a key protein on LDL called apolipoprotein B (apoB) is an important contributor for heart disease risk.

How important is the LDL particle number?

Atherogenic particle number above 130 mg/dL or LDL-P above 2000 nmol/L is considered a “risk enhancing factor” when determining your overall risk for suffering a cardiovascular event.

What is good LDL peak size?

For LDL particle size, we classified patients from 18.0 to 21.2 as phenotype B and patients from 21.3 to 23.0 as phenotype A (4). For LDL-P, we categorized patients as optimal (<1,100), near optimal (1,101–1,399), borderline-high (1,400–1,799), high (1,800–2,100) or very high (>2,100).