What is peritoneal membrane test?

The peritoneal equilibration test (PET) is a semiquantitative assessment of peritoneal membrane transport function in patients on peritoneal dialysis [1,2]. The solute transport rates are assessed by the rates of their equilibration between the peritoneal capillary blood and dialysate.

How is peritoneal equilibration test performed?

You use a catheter (plastic tube) to fill your belly with sterile PD fluid (dialysate). Tiny capillary blood vessels in your peritoneum act as filters. Wastes and extra water flow from your blood into the dialysate, which you then drain out. You can exchange used fluid for fresh by hand or with a cycler machine.

What is peritoneal membrane failure?

This most common form of ultrafiltration failure arises as a consequence of changes in the peritoneal membrane over time causing a transition to a very rapid transport status. This results in the rapid dissipation of the osmotic gradient and consequently poor ultrafiltration.

What is the peritoneal membrane used for?

The peritoneal membrane is the smooth, transparent membrane that lines the abdominal cavity and contains the internal organs of the abdomen and pelvis, such as the stomach and large intestine. The peritoneal membrane helps to protect and separate the internal structures of the abdomen and pelvis.

How often is PD adequacy checked?

An adequacy test is done about 1 month after you finish your peritoneal dialysis training. It is also done every 6 months after that. Each time there is a change in your dialysis prescription your doctor may request your test be repeated.

What is the difference between APD and CAPD?

Continuous ambulatory peritoneal dialysis (CAPD) involves performing the PD exchanges manually whereas, automated PD (APD) is a broad term that is used to refer to all forms of PD employing a mechanical device to assist the delivery and drainage of dialysate.

What does a low UF mean on PD?

Ultrafiltration failure means there is not enough fluid crossing the peritoneal membrane. Some things that can cause ultrafiltration to fail include uremia (high blood urea nitrogen), peritonitis (infection of the peritoneal membrane), and high dextrose PD solution (especially 4.25%).

What is a normal UF in peritoneal dialysis?

It states that UF failure is present when netUF is less than 400 mL after drainage of a 4% (3.86 or 4.25%, depending on the pharmacopeia) dialysis solution with an intraperitoneal stay of 4 h.

Where is the peritoneal membrane located?

abdominal cavity
The peritoneum is the serous membrane that lines the abdominal cavity. It is composed of mesothelial cells that are supported by a thin layer of fibrous tissue and is embryologically derived from the mesoderm.

Why is the peritoneal membrane used in dialysis?

Peritoneal dialysis uses the peritoneal membrane as an endogenous exchange membrane to remove solutes and water from the body fluids of patients with end-stage renal disease. The efficiency of this system is variable, with the solute transport up to three times more effective in some patients than in others (1).

Can I skip a day on PD dialysis?

One of the big problems with PD is that patients sometimes do not perform all of the exchanges recommended by their medical team. They either skip exchanges or sometimes skip entire treatment days when using CCPD. Skipping PD treatments has been shown to increase the risk of hospitalization and death.