What is the common symptom associated with agenesis of the corpus callosum?

Agenesis of the corpus callosum (ACC) is a birth defect in the brain. The corpus callosum, a bundle of nerves connecting the left and right sides of the brain, is either missing or partially missing. Symptoms range from minor intelligence issues to developmental delays and seizures.

How is the corpus callosum related to epilepsy?

The corpus callosum is a major structure permitting exchange of information between the two hemispheres, or halves, of the brain. In some children, seizures may spread from one hemisphere to the other through the corpus callosum. This may result in generalized seizures, including ‘drop attacks’ or atonic seizures.

Does cutting the corpus callosum stop seizures?

The procedure prevents seizures from spreading from one half of the brain to the other. Corpus callosotomy surgery does not completely eliminate seizures, but it prevents them from affecting the entire brain and muscles on both sides of the body.

Can ACC cause seizures?

The first symptoms of ACC are usually seizures, which may be followed by feeding problems and delays in holding the head erect, sitting, standing, and walking. The seizures may be caused by a very common disorder called infantile spasms, which is associated with ACC.

Is agenesis of corpus callosum a disability?

Corpus callosum agenesis or dysgenesis (CCA) can be diagnosed antenatally, either isolated or associated with other cerebral or extra-cerebral malformations….Corpus Callosum Agenesis and Intellectual Disability (ACCREM)

Observational Model: Cohort
Time Perspective: Prospective

Is there a surgery to cure seizures?

Epilepsy surgery is most effective when seizures always occur in a single location in the brain. Epilepsy surgery is not the first line of treatment but is considered when at least two anti-seizure medications have failed to control seizures.