What is DMSO in organic chemistry?

Dimethyl sulfoxide (DMSO) is a widely used solvent that is miscible with water and a wide range of organic solvents. It goes by several names, including methyl sulfoxide, sulfinylbismethane, and dozens of trade names.

What does the reagent DMS do?

It is used as a presulfiding agent to control the formation of coke and carbon monoxide in ethylene production. DMS is also used in a range of organic syntheses, including as a reducing agent in ozonolysis reactions. It also has a use as a food flavoring component.

What does DMSO do in a chemical reaction?

Dimethyl sulfoxide can produce an explosive reaction when exposed to acyl chlorides; at a low temperature, this reaction produces the oxidant for Swern oxidation. DMSO can decompose at the boiling temperature of 189 °C at normal pressure, possibly leading to an explosion.

What is the function of DMSO?

Dimethyl sulfoxide (DMSO) is an organic polar aprotic molecule with an amphipathic nature that is ideal for dissolving poorly soluble polar and non-polar molecules. DMSO is widely used as solvent in toxicology and pharmacology, for cryopreservation of cells, and as penetration enhancer during topological treatments.

What does dimethyl sulfate do to DNA?

DNA Footprinting Dimethyl sulfate (DMS) methylates guanine residues at the N7 position (accessible through the major groove of DNA) and, with a reduced efficiency, adenine residues at the N3 position (protruding through the minor groove). DMS can be used for methylation protection or methylation interference assays.

Is DMSO hydrophobic?

The formation of an ordered hydration structure around the Me groups of DMSO provides clear evidence of ‘hydrophobic’ hydration. Increasing the concentration of DMSO enhances the structure of water around the Me groups of DMSO, with stronger water–water hydrogen bonds.

Why is DMSO universal solvent?

Dimethyl sulfoxide (DMSO) is an important aprotic solvent that can solubilize a wide variety of otherwise poorly soluble polar and nonpolar molecules. This, coupled with its apparent low toxicity at concentrations <10%, has led to its ubiquitous use and widespread application.

Is DMSO an oxidizing agent?

Effect of Added Radical Traps on the Rate of Oxidation. The above data indicate that dimethyl sulfoxide is a mild chemical oxidant for porous Si. In organic and biological oxidations, DMSO is known to deliver an O atom to the substrate.

Is DMSO a positive or negative control?

In this experiment DMSO was used as a negative control and also proved to be a safe solvent, which offered no interference with the results obtained in the assay.

What is dimethyl sulfide?

Dimethyl sulfide was the primary sulfur species determined in emissions from oat, corn, soybean, orchard grass, purple clover, and alfalfa fields, with the total sulfur emission rate ranging from 0.007 to 0.273 g sulfur /sq m/yr (1). Dimethyl sulfide has been identified in volatile emissions from evergreen cypress trees (2).

What is the Koc of dimethyl sulfide?

The Koc of dimethyl sulfide is estimated as 6.3 (SRC), using a water solubility of 22,000 mg/L (1) and a regression-derived equation (2). According to a classification scheme (3), this estimated Koc value suggests that dimethyl sulfide is expected to have very high mobility in soil.

Does dimethyl sulfide bioconcentrate in aquatic organisms?

According to a classification scheme (3), this BCF suggests the potential for bioconcentration in aquatic organisms is low (SRC). The Koc of dimethyl sulfide is estimated as 6.3 (SRC), using a water solubility of 22,000 mg/L (1) and a regression-derived equation (2).

Is dimethyl sulfide a volatile sulfur compound in mouth air?

Emergency Care For Hazardous Materials Exposure. 3Rd edition, Elsevier Mosby, St. Louis, MO 2005, p. 480 /CASE REPORTS/ The purpose of this report is to document the presence of dimethyl sulfide in mouth air as the predominant volatile sulfur compound (VSC) in an asthmatic patient who was regularly taking suplatast tosilate.