What is chylomicron and what is its function?
What is chylomicron and what is its function?
Chylomicrons are produced for the purpose of transporting dietary triglycerides and cholesterol absorbed by intestinal epithelia. Chylomicron assembly originates in the intestinal mucosa. Excretion into the plasma is facilitated through the lymphatic system.
What is the most abundant component of chylomicrons?
1. Most of our dietary fats are incorporated into chylomicrons in the intestine. The most abundant component of chylomicrons is which one of the following? Chylomicrons transport dietary lipids, and >80% of the chylomicron is triglyceride.
What are the 5 compounds assembled into chylomicrons?
Chylomicrons. These are large triglyceride rich particles made by the intestine, which are involved in the transport of dietary triglycerides and cholesterol to peripheral tissues and liver. These particles contain apolipoproteins A-I, A-II, A-IV, A-V, B-48, C-II, C-III, and E.
What are the components of remnant chylomicrons?
As a result, a new particle called a chylomicron remnant is formed. This particle is enriched in cholesteryl ester and fat-soluble vitamins and contains apoB-48 and apoE. It is rapidly removed from the circulation by the liver. ApoE is the moiety required for rapid hepatic removal.
Why are chylomicrons made?
Chylomicrons (Fig. 20-14) are formed in the intestinal epithelium to transport long-chain triglycerides to the tissues. Medium- and short-chain fats are transported directly to the liver through the portal circulation without packaging into lipoprotein particles.
What are chylomicrons coated with?
Thus, chylomicrons are fat droplets coated with steroids and proteins. Chylomicrons are conjugated protein particles that arise from the endoplasmic reticulum of the cells. Chylomicrons consist of triglycerides, phospholipids, sterol, and proteins.
Which of the following is counted under the composition of chylomicrons?
Triacylglycerol, phospholipids, cholesterol esters and absorbed fat soluble vitamins are transported from mucosal cells to the lymph in the form of lipoprotein known as chylomicrons. The composition of chylomicrons is: triacylglycerol (85-90%) cholesterol and cholesterol ester (5%)
Where is chylomicron made?
intestinal cells
Chylomicrons are made only in intestinal cells, whereas VLDLs are also synthesized in the liver. To form a chylomicron, triglycerides, fat-soluble vitamins, and cholesterol are coated with a layer of apolipoprotein (apo A and B types),77 cholesterol ester, and phospholipids.
How is chylomicron formed?
Origin. Chylomicrons are formed in the endoplasmic reticulum in the absorptive cells (enterocytes) of the small intestine. Apolipoproteins are significant in the synthesis and metabolism of chylomicrons.
How is chylomicrons formed?
Intestinal Pathway Chylomicron is assembled in the intestinal epithelium. Absorbed fatty acids are re-esterified to form TGs, and they are added to apo B48 to form chylomicrons.
