What is a Mesonephric adenocarcinoma?

Mesonephric adenocarcinoma (MNAC) is an extremely rare and highly malignant tumor in the female reproductive system. It is considered to originate from the embryonal remnants of mesonephric ducts (also known as Wolffian ducts).

What is grade 3 endometrial adenocarcinoma?

High-risk endometrial cancer Grade 3 tumors are considered high-risk. They often spread to other parts of the body. Uterine papillary serous, clear cell, and carcinosarcoma are three subtypes of endometrial cancer that are considered grade 3.

What is Figo grade 2 endometrioid adenocarcinoma?

International Federation of Gynecology and Obstetrics (FIGO) Grade 2 endometrial endometrioid adenocarcinoma carries a 88% 5-yr survival rate. They are defined by >5% but <50% solid epithelial component. A small subset may display <5% solid growth, but marked nuclear atypia and are designated Grade 2.

What is Grade 1 cancer of the uterus?

Grades 1 and 2 endometrioid cancers are type 1 endometrial cancers. Type 1 cancers are usually not very aggressive and they don’t spread to other tissues quickly. Type 1 endometrial cancers are thought to be caused by too much estrogen.

What is mesonephric duct?

The mesonephric duct, also known as the Wolffian duct, is an embryonal paired structure in mammals that differentiates into the epididymis, vas deferens and seminal vesicles in males.

What is the 5 year survival rate of a stage 1 Grade 1 adenocarcinoma of the endometrium?

Patients with stage I endometrial carcinoma, treated with total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO) and postoperative radiotherapy (RT) tailored to prognostic factors, have 5-year overall survival rates of 80% to 90%, 5-year cancer-specific survival of 90% to 95%, and locoregional …

What does FIGO Grade 1 of 3 mean?

Differentiation: The cells are given a score of 1–3 based on how they look. A score of 1 means the cancer cells look very similar to normal cells. A score of 3 means the cells look very abnormal.

What happens to mesonephric duct in females?

Development. In both male and female the mesonephric duct develops into the trigone of urinary bladder, a part of the bladder wall, but the sexes differentiate in other ways during development of the urinary and reproductive organs.

Do mesonephric ducts degenerate in females?

In females, the mesonephric tubules and WDs degenerate, although remnants may be present in the form of an appendix vesiculosa, epoophoron, paroophoron or duct of Gartner.