Can pilocarpine eye drops be used to treat dry mouth?

This should be read in conjunction with the attached manufacturer’s patient information leaflet. In palliative care, pilocarpine eye drops are sometimes prescribed to be taken by mouth to treat dry mouth conditions.

How do you use pilocarpine drops for dry mouth?

How to use Pilocarpine Hcl

  1. Take this medication by mouth with or without food, usually 3-4 times daily, or as directed by your doctor.
  2. Dosage is based on your medical condition and response to treatment.
  3. You may continue to drink water or use saliva substitutes as needed for moisture in your mouth.

How long does it take pilocarpine to start working?

Although the data show that pilocarpine-induced stimulation of salivary flow occurred within 30 minutes of ingestion of the first dose and was maintained through week 12, the onset of subjective benefit for various symptoms took 6 to 12 weeks.

How effective is pilocarpine for dry mouth?

Trial medication The dose was chosen based on previous studies [15] and a previous report that pilocarpine (15-30 mg/day) improves symptoms in about 50% of patients, compared 25% of patients taking placebo [20].

Does pilocarpine help burning mouth syndrome?

This provides the probability that mild hyposalivation may exist as one of the causes for the complaint of oral dryness and also suggests that the use of a sialogogue (for example, Pilocarpine) at times of rest may be helpful in burning mouth syndrome.

Is pilocarpine safe to take?

Caution with gallbladder or kidney problems Pilocarpine (Salagen) can cause muscle spasms in or around your gallbladder or kidneys. If you have gallstones or gallbladder problems, or kidney stones, this can lead to problems, such as pain, inflammation, and blockage.

Can you use pilocarpine long term?

The optimal dose of oral pilocarpine, which was less likely to cause side effects, was 5 mg four times daily. A recent multi-center study in SS patients suggests that oral pilocarpine is effective and safe for long-term administration.

Is pilocarpine eye drops safe?

Pilocarpine eye drops or eye gel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: blurred or dim vision. stinging, burning, or discomfort in the eye.

Can Sjogren’s cause burning tongue?

Patients with SS may describe a burning sensation of the mouth and/or the tongue88. While the source of this discomfort is not well understood, it is possible that this sensation may be related to the neurologic manifestations of SS.

Does pilocarpine cause dry mouth?

It is important that you visit your dentist regularly even though this medicine may make your dry mouth feel better. Having a dry mouth condition makes you more likely to have dental and other mouth problems.