Can Plavix cause thrombotic thrombocytopenic purpura?

A medical journal announced that the anticlotting drug Plavix may cause a rare blood disorder called thrombotic thrombocytopenic purpura, or TTP. The report was released two months early because of this dangerous side effect.

What medication causes thrombotic thrombocytopenic purpura?

Drugs such as mitomycin, cyclosporine, cisplatin, bleomycin, quinine, and ticlopidine have been associated with HUS and TTP.

Can thrombotic thrombocytopenic purpura be cured?

Adults diagnosed with mild thrombocytopenic purpura may recover without any intervention. You will need treatment if the disorder causing purpura doesn’t go away on its own. Treatments include medications and sometimes a splenectomy, or surgery to remove the spleen.

Can clopidogrel cause blood spots?

This medicine may increase your chance of bleeding or bruising. Check with your doctor right away if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin.

Does Plavix cause excessive bruising?

Bruising is one of the most common side effects of Plavix. Bruises form when small blood vessels under the skin break, leading to localized bleeding. Because Plavix works by thinning the blood, you might experience bruising more easily and often while taking this medication.

How is thrombotic thrombocytopenic purpura diagnosed?

How is thrombotic thrombocytopenic purpura diagnosed?

  1. Complete blood count (CBC). A CBC measures the number of platelets as well as the number of red blood cells and white blood cells.
  2. Bilirubin test.
  3. Blood smear.
  4. Urine or kidney function tests.
  5. Creatinine test.
  6. Lactate dehydrogenase test.
  7. ADAMTS13 assay.

What are the signs and symptoms of purpura?

Symptoms of purpura

  • low platelet count, which may lead to increased bleeding after an injury, bleeding gums or nose, or blood in urine or bowel movements.
  • sore, swollen joints, particularly in the ankles and knees.
  • gut problems such as nausea, vomiting, diarrhea, or stomach pain.

When should I be concerned about purpura?

Patients who experience purpura with any of the following symptoms should seek medical treatment: low platelet count, which may lead to increased bleeding after an injury, bleeding gums or nose, or blood in urine or bowel movements. sore, swollen joints, particularly in the ankles and knees.

How do you prevent purpura?

Senile purpura is not always preventable, but people can use sunscreen and protect their skin from sun damage as much as possible. Sunscreens, long clothing, and hats will not reverse damage caused by sun exposure, but they can help prevent additional damage.

Can clopidogrel cause skin problems?

Clopidogrel is a new antiplatelet prescribed for the secondary prevention of atherosclerotic events. The literature shows that the clinical manifestations of clopidogrel hypersensitivity include urticaria1, skin rash2-4, and angioedema5.

What is the most serious adverse effect of clopidogrel?

The main side effect of clopidogrel is bleeding more easily than normal. You may have nosebleeds, heavier periods, bleeding gums or bruising. You can drink alcohol with clopidogrel. But do not drink too much while taking this medicine.

What are the side effects of long term use of Plavix?

Side effect details

  • Allergic reaction. As with most drugs, some people can have an allergic reaction after taking Plavix.
  • Bruising. You may have bruising while you’re taking Plavix.
  • Skin rash. It’s possible to have skin rashes while you’re using Plavix.
  • Nosebleeds.
  • Headaches.
  • Blood in your urine.
  • Itching.
  • Diarrhea.

Can blood thinners cause purpura?

People who take certain drugs, such as blood thinners or steroids, on a regular basis may be more likely to experience purpura. Non-steroidal anti-inflammatory drugs (NSAIDs) may also contribute to the condition.

When should I worry about purpura?

Do blood thinners cause purpura?