Do seizure meds cause osteoporosis?

Some people who take epilepsy medicines are at risk of decreased bone mineral density. This condition is called osteoporosis. It is a condition that can weaken bones, making them fragile and more likely to break.

What seizure meds cause bone loss?

The AEDs most commonly reported to cause decreased bone mineral density and disorders of bone metabolism are inducers of the cytochrome P450 enzyme system (phenobarbital, phenytoin, carbamazepine, primidone). More recent studies also suggest that valproate, an enzyme inhibitor, causes abnormalities in bone health.

What medications make osteoporosis worse?

High doses of corticosteroids.

  • High doses of thyroid medicines.
  • Medicines that reduce levels of sex hormones.
  • Certain diabetes medicines.
  • Certain stomach medicines, such as proton pump inhibitors or antacids containing aluminum.
  • Certain antidepressants.
  • Mood stabilizers containing lithium.

    • Does Keppra affect bone density?

    The level of levetiracetam dosage (low or high) was not associated with BMD or bone metabolism. The results of this study suggest that levetiracetam monotherapy does not adversely affect bone health. The currently available data do not support a negative association between levetiracetam and bone health.

    Can you take vitamin D with epilepsy medication?

    Vitamin D May Help Seizure Control Supplemental vitamin D may be necessary for people who have these risk factors to maintain normal blood levels. A study published in 2012 showed that correcting vitamin D deficiency reduced seizures in people with epilepsy.

    Which drugs inhibit the breakdown of bone?

    Medications to Prevent Fragility Fractures

    • Alendronate Sodium or Alendronate Sodium plus Vitamin D3 (Fosamax®, Fosamax Plus D and Binosto®)
    • Ibandronate Sodium (Boniva®)
    • Risedronate Sodium (Actonel®and Atelvia™)
    • Zoledronic Acid (Reclast®)
    • Denosumab (Prolia®)
    • Calcitonin-Salmon (Fortical®and Miacalcin®)

    What medications interfere with calcium absorption?

    Common culprits include medications used to treat heartburn and “gastroesophageal reflux disorder” (GERD), such as omeprazole (Prilosec), lansoprazole (Prevacid), and esomeprazole (Nexium). These medications decrease the production of stomach acid, which leads to decreased calcium absorption.

    Can I take Vitamin D3 with Keppra?

    Interactions between your drugs No interactions were found between Keppra and Vitamin D3.

    What medications decrease bone density?

    Many drugs can affect bone metabolism. As an example, heparin, warfarin, cyclosporine, glucocorticoids, medroxyprogesterone acetate, cancer drugs, and thyroid hormone can cause bone loss, while thiazide diuretics can minimize bone loss [1,2]. This topic will review the skeletal effects of some of these drugs.

    Does Keppra affect vitamin D?

    No interactions were found between Keppra and Vitamin D3.

    How much Vitamin D3 should I take for epilepsy?

    In both groups, high dose vitamin D3 (8000 to 16000 IU/day) was associated with reductions in seizure frequency 33% reduction in mean seizure frequency from baseline.