How do you give cytarabine injection?

Cytarabine Injection may be given by intravenous infusion or injection or subcutaneously. Thrombophlebitis has occurred at the site of drug injection or infusion in some patients, and rarely patients have noted pain and inflammation at subcutaneous injection sites.

What is the use of cytarabine injection?

Cytarabine is used alone or with other chemotherapy drugs to treat certain types of leukemia (cancer of the white blood cells), including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and chronic myelogenous leukemia (CML).

How is cytarabine given?

Cytarabine may be given as an infusion into the vein (intravenous or IV). Another method it is given is by intrathecal infusion. This method is used when drugs need to reach the cerebrospinal fluid (CSF) the fluid that is surrounding the brain and spinal cord, the drug is infused directly into the spinal fluid.

How do you administer IV cytarabine?

Cytarabine, under strict medical surveillance, is administered as monotherapy or in combination with other cytostatics, 2-3 g/m2, as intravenous infusion, for 1-3 hours every 12 hours for 2-6 days. (Total of 12 doses per cycle). A total treatment dose of 36 g/m2 should not be exceeded.

How effective is cytarabine?

The overall survival data with the use of cytarabine in conventional and high dose regimen is approximately 40% with remission rates of 70–80% and relapse-free 5 years survival of 40-70%[15]. Standard intensive treatment improves early death rates and long-term survival compared with palliation.

Where do you inject cytarabine?

Cytarabine 100 mg/ml Injection is a ready to use injection and can be administered by the intravenous and subcutaneous routes. Cytarabine 100 mg/ml Injection should not be administered by the intrathecal route due to the slight hypertonicity of this formulation.

Is cytarabine a chemotherapy?

Cytarabine is a type of chemotherapy drug and is also known by its brand name, Ara C. It is a treatment for: acute leukaemias (cancers of the blood)

Does cytarabine need central line?

Drugs into your bloodstream You might need a central line. This is a long plastic tube that gives the drugs into a large vein, either in your chest or through a vein in your arm. It stays in while you’re having treatment, which may be for a few months.