How does eukaryotic transcription is terminated?

The termination of transcription is different for the different polymerases. Unlike in prokaryotes, elongation by RNA polymerase II in eukaryotes takes place 1,000–2,000 nucleotides beyond the end of the gene being transcribed. This pre-mRNA tail is subsequently removed by cleavage during mRNA processing.

How does termination work in eukaryotes?

RNA Polymerase II terminates transcription at random locations past the end of the gene being transcribed. The newly-synthesized RNA is cleaved at a sequence-specified location and released before transcription terminates.

What is the terminator sequence in eukaryotes?

The terminator is a region of DNA that includes the sequence that codes for the Rho binding site in the mRNA, as well as the actual transcription stop point (which is a sequence that causes the RNA polymerase to pause so that Rho can catch up to it).

Do eukaryotes have terminators?

In eukaryotes In eukaryotic transcription of mRNAs, terminator signals are recognized by protein factors that are associated with the RNA polymerase II and which trigger the termination process.

How does the termination of transcription differ between eukaryotes and prokaryotes?

Termination in prokaryotes is done by either rho-dependent or rho-independent mechanisms. In eukaryotes transcription is terminated by two elements: a poly(A) signal and a downstream terminator sequence (7).

How is transcription terminated in prokaryotic cells?

Transcription termination in prokaryotes can be rho-independent (intrinsic terminators exist in the RNA polymerase) and rho-dependent, i.e., the RNA polymerase requires the cofactor rho for termination of transcription. The terminator regions in various systems have similar structures.

Which protein helps in termination transcription?

Escherichia coli protein Rho is required for the factor-dependent transcription termination by an RNA polymerase and is essential for the viability of the cell. It is a homohexameric protein that recognizes and binds preferably to C-rich sites in the transcribed RNA.

How is transcription terminated in prokaryotes?

How is transcription termination different in prokaryotes and eukaryotes?

Eukaryotes contain mRNAs that are monocystronic. Termination in prokaryotes is done by either rho-dependent or rho-independent mechanisms. In eukaryotes transcription is terminated by two elements: a poly(A) signal and a downstream terminator sequence (7).