Is Listeria sensitive to meropenem?

Abstract. Listeria monocytogenes is highly susceptible to meropenem in vitro, but data on the efficacy of meropenem in clinical cases of listeriosis are scarce.

What antibiotics treat Listeria in pregnancy?

Penicillin, ampicillin, and amoxicillin have been used most extensively in the treatment of listeriosis. Most experts recommend 6 g or more per day of ampicillin for treatment during pregnancy. This dosage provides adequate intracellular penetration and crosses the placenta in adequate amounts.

How is listeria infection treated?

Treatment of listeria infection varies, depending on the severity of the signs and symptoms. Most people with mild symptoms require no treatment. More-serious infections can be treated with antibiotics.

How is Listeria meningitis treated?

Ampicillin with or without an aminoglycoside remains the best treatment for meningitis caused by L monocytogenes.

Is Listeria monocytogenes antibiotic resistant?

Despite efficient antibiotic therapy, listeriosis represents a public health problem since it is fatal in up to 30% of cases (16, 26). In general, isolates of L. monocytogenes, as well as strains of other Listeria spp., are susceptible to a wide range of antibiotics except cephalosporins and fosfomycin (23, 24).

Does ceftriaxone cover Listeria?

Selected Drug Comments Ceftriaxone/cefotaxime. Cephalosporins do not have activity against Listeria. This is important to remember in the empiric selection of drugs for pyogenic meningitis. Often added to ampicillin to achieve synergy.

What if I get listeria while pregnant?

During the first trimester of pregnancy, listeriosis may cause miscarriage. As the pregnancy progresses to third trimester, the mother is more at risk. Listeriosis can also lead to premature labor, the delivery of a low-birth-weight infant, or infant death.

How long do you take antibiotics for listeria?

In either case, if the diagnostic test comes back positive for a listeria infection, the “standard” treatment is a 14- to 21-day course of intravenous (IV) antibiotics using the drugs ampicillin and gentamicin, which provide more protection against the harmful bacteria than oral doses.

Does Cipro treat Listeria?

Among food-related infections, listeriosis has a high case-fatality rate (∼25%) [1]. Ciprofloxacin has been demonstrated to be bacteriostatic against Listeria [4] in usual concentrations. Of the “older” quinolones, ciprofloxacin is the most effective against L.

Does azithromycin treat Listeria?

Antibiotics effective against Listeria species include ampicillin, vancomycin, ciprofloxacin, linezolid and azithromycin. However, early diagnosis is the exception rather than the rule, since the first signs of a case or an outbreak are reports of stillbirth or serious infections resembling listeriosis.

Is Listeria resistant to ceftriaxone?

The majority of L. monocytogenes isolates were resistant to oxacillin (99%, 89/90) and ceftriaxone (72%, 65/90), while few isolates were resistant to clindamycin (21%, 19/90) and ciprofloxacin (2%, 2/90).

Is Listeria sensitive to penicillin?

All strains were susceptible to erythromycin, clarithromycin, streptomycin, gentamicin, vancomycin, imipenem, trimethoprim, and chloramphenicol, while all strains were resistant to nalidixic acid, ampicillin, penicillin G, linezolid, and clindamycin.