What are the causes of neutropenia?

The causes of neutropenia include:

  • Problem in the production of neutrophils in the bone marrow.
  • Destruction of neutrophils outside the bone marrow.
  • Infection.
  • Nutritional deficiency.

What is neutropenia Pubmed?

Neutropenia, a deficiency of these cells, predisposes to infection, chiefly by organisms resident on body surfaces. The risk of infection is greatest with severe neutropenia, defined by an absolute blood neutrophil count (ANC) less than 0.5 x 10(9)/L.

What level is neutropenia?

In adults, a count of 1,500 neutrophils per microliter of blood or less is considered to be neutropenia, with any count below 500 per microliter of blood regarded as a severe case.

What is normal neutrophil count?

White blood cells (WBCs) The most important infection-fighting WBC is the neutrophil . The number doctors look at is called your absolute neutrophil count (ANC). A healthy person has an ANC between 2,500 and 6,000. The ANC is found by multiplying the WBC count by the percent of neutrophils in the blood.

How is neutropenia diagnosed?

How will a doctor diagnose neutropenia? The most common test is a simple blood test known as a complete blood count. In some cases, such as when a certain disease is suspected, the doctor might want to test your bone marrow.

What drugs cause neutropenia?

There are many medications that can result in drug-induced neutropenia. The most common are carbimazole, clozapine, dapsone, dipyrone, methimazole, penicillin G, procainamide, propylthiouracil, rituximab, sulfasalazine, and ticlopidine.

What is the main function of neutrophil?

When microorganisms, such as bacteria or viruses, enter the body, neutrophils are one of the first immune cells to respond. They travel to the site of infection, where they destroy the microorganisms by ingesting them and releasing enzymes that kill them. Neutrophils also boost the response of other immune cells.

Who is at risk for neutropenia?

Some people with cancer are more likely to develop neutropenia, including: People who are age 70 or older. People with a lowered immune system from other causes, such as having HIV or an organ transplant.