What are the chemical properties of ibuprofen?
What are the chemical properties of ibuprofen?
The trivial name ibuprofen comes from fragments of its chemical name, (±)-2-(p-isobutylphenyl)propionic acid….Ibuprofen fast facts.
| CAS Reg. No. | 15687-27-1 |
|---|---|
| Empirical formula | C13H18O2 |
| Appearance | Colorless crystals |
| Melting point | 75–77 ºC |
| Water solubility | 21 mg/L |
What is the chemical structure of ibuprofen?
Ibuprofen | C13H18O2 – PubChem.
What functional groups are in the structure of ibuprofen?
Question 2 What functional groups does ibuprofen have? A carboxylic acid and an aromatic ring.
What is the chemical name of ibuprofen?
(RS)-2-(4-(2-methylpropyl)phenyl)propanoic acidIbuprofen / IUPAC ID
What is the function of ibuprofen?
Nonprescription ibuprofen is used to reduce fever and to relieve minor aches and pain from headaches, muscle aches, arthritis, menstrual periods, the common cold, toothaches, and backaches. Ibuprofen is in a class of medications called NSAIDs.
What is the mechanism of ibuprofen?
Mechanism of action Ibuprofen is a non-selective inhibitor of an enzyme called cyclooxygenase (COX), which is required for the synthesis of prostaglandins via the arachidonic acid pathway. COX is needed to convert arachidonic acid to prostaglandin H2 (PGH2) in the body. PGH2 is then converted to prostaglandins.
Why is ibuprofen an organic compound?
Structure for FDB022743 (Ibuprofen) Belongs to the class of organic compounds known as phenylpropanoic acids. Phenylpropanoic acids are compounds with a structure containing a benzene ring conjugated to a propanoic acid.
What is pharmacodynamics of ibuprofen?
Pharmacodynamics/Mechanism of action: Ibuprofen possesses analgesic, antipyretic and anti-inflammatory properties, similar to other non-steroidal anti-inflammatory drugs (NSAIDs).
What are the raw materials of ibuprofen?
Raw Materials: Isobutyl Benzene (IBB), Sodium Metal, Aluminium Chloride and Sodium Dichromate.
What kind of bond is ibuprofen?
One of the key features defining the ibuprofen structure is the doubly intermolecular O-HO[double bond, length as m-dash]C hydrogen bond in cyclic dimers as know from carboxylic acids and confirmed by X-ray analysis.
What is the process of ibuprofen?
Ibuprofen, on the other hand, is removed from your body by your kidneys. Taking it for a long time can cause kidney damage and stomach bleeding.
How do you manufacture ibuprofen?
Ibuprofen was successfully synthesized from the starting materials isobutylbenzene and acetic anhydride through a Friedel-Crafts acylation, carbonyl reduction, chloride substitution, and Grignard reaction. The structure and purity of the product were supported by IR, 1H NMR, and melting point analysis.
How many bonds are present in the structure of ibuprofen shown?
Chemical Structure Description The ibuprofen molecule contains a total of 33 bond(s) There are 15 non-H bond(s), 7 multiple bond(s), 4 rotatable bond(s), 1 double bond(s), 6 aromatic bond(s), 1 six-membered ring(s), 1 carboxylic acid(s) (aliphatic) and 1 hydroxyl group(s).
Who manufactures ibuprofen?
ADVIL by Wyeth Pharmaceuticals Company
| Active Ingredient/Active Moiety | ||
|---|---|---|
| Ingredient Name | Basis of Strength | Strength |
| IBUPROFEN (IBUPROFEN) | IBUPROFEN | 200 mg |
What type of bond is ibuprofen?
How many single bonds are in ibuprofen?
How is ibuprofen manufactured?
Ibuprofen is produced using three reactors: in the first PFR, Friedel-Crafts acylation converts isobutyl benzene (IBB) into intermediate 2A, then transformed in the second PFR (by 1,2-aryl migration) into intermediate 3A.
Who patented ibuprofen?
Chemist John Nicholson and pharmacologist Stewart Adams developed ibuprofen during the 1950s and 1960s at Boots Pure Drug Co. in England. Today, ibuprofen is a popular first-line treatment for safely reducing pain, fever and inflammation, and it is available in more than 80 countries.
What intermolecular forces are present in ibuprofen?
Ibuprofen as white crystalline Bonds: This organic chemical demonstrates covalent bonding with the intermolecular forces of dipole-dipole forces, London dispersion forces and even hydrogen bonding. The hydrogen bonding only occurs with the oxygen atoms to the hydrogen atoms of the molecule.
How is ibuprofen formed?
Ibuprofen was successfully synthesized from the starting materials isobutylbenzene and acetic anhydride through a Friedel-Crafts acylation, carbonyl reduction, chloride substitution, and Grignard reaction.
