What causes lichen amyloidosis?

Chronic friction is a common etiological cause of lichen amyloidosis and treatment is usually directed at relieving the associated pruritus. Sedating antihistamines may help with relieving the itch, not because of their inherent antihistamine effects, but because of their inherent sedating qualities.

Is cutaneous amyloidosis serious?

Very rarely, nodular amyloidosis progresses to a life-threatening condition called systemic amyloidosis, in which amyloid deposits accumulate in tissues and organs throughout the body.

How do you get rid of lichen amyloidosis?

The treatment of lichen and macular amyloidosis is focused on relieving itch. Sedating antihistamines can be moderately effective. Topical and intralesional steroids may provide some relief if used with other treatments. Other treatments include topical dimethyl sulfoxide (DMSO) and phototherapy (UVB or PUVA).

How common is lichen amyloidosis?

It is more common in males than in females and occurs most frequently in persons aged 50-60 years. Lichen amyloidosis accounts for approximately 10% of cases of PLCA. The pathogenesis remains undetermined, but it is considered a secondary process following chronic scratching associated with primary disease.

Is lichen amyloidosis rare?

Lichen amyloidosis is a rare chronic form of cutaneous amyloidosis (see this term), a skin disease characterized by the accumulation of amyloid deposits in the dermis, clinically characterized by the development of pruritic, often pigmented, hyperkeratotic papules on trunk and extremities, especially on the shins, and …

Is amyloidosis an auto immune disease?

Additional Testing for AA Amyloidosis An underlying condition is one medical condition that causes another one. With AA amyloidosis, the underlying condition is an autoimmune disease or chronic infection.

What vitamins are good for amyloidosis?

One animal study suggested that high doses of vitamin C may help the body break down amyloid and prevent amyloidosis from worsening.

How is lichen amyloidosis diagnosed?

The diagnosis can usually be made clinically, particularly in patients with the classic presentation. A skin biopsy should be reserved for evolving lesions. Lichen amyloidosis is a chronic condition without potential for malignant transformation.

What does cutaneous amyloidosis look like?

Overview. Lichen amyloidosis – multiple itchy, raised spots which are scaly and red/brown in color. This rash generally affects the shins, thighs, feet and forearms. Macular amyloidosis – mild to severely itchy, flat, dusky-brown or greyish colored spots that may come together to form patches of darkened skin.

How is amyloidosis diagnosed?

A biopsy that shows amyloid deposits is the best confirmation of amyloidosis. The physician usually takes the tissue sample from abdominal fat or rectum. Sometimes, the tissue comes from damaged organs such as the liver, heart, kidney or intestines.