What does dengue NS1 positive mean?

A positive NS1 test result confirms dengue virus infection without providing serotype information. A negative NS1 test result does not rule out infection. People with negative NS1 results should be tested for the presence of dengue IgM antibodies to determine possible recent dengue exposure.

What is the severity of dengue?

About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and even death. If you have had dengue in the past, you are more likely to develop severe dengue. Infants and pregnant women are at higher risk for developing severe dengue.

What is the normal range of dengue NS1 antigen?

An NS1 Ag level varies from 0.5-2 μg/ml in acute-phase serum samples, to less than 0.04 μg/ml in convalescent phase serum [11]. The requirement of paired sera, subsequently in convalescent phase, if negative in acute phase also delays diagnosis.

What are the four stages of dengue?

Dengue begins abruptly after a typical incubation period of 5–7 days, and the course follows 3 phases: febrile, critical, and convalescent.

Is dengue NS1 curable?

There is no dengue cure available. The disease is usually self-limiting and goes away after two weeks in a typical infection. Some people, however, may become critical and have severe internal bleeding or dengue haemorrhagic fever.

What is dengue IgG IgM NS1?

Dengue Antigen NS1, IgG and IgM test detects the non-structural protein component (NS1) of the dengue virus and the antibodies (IgG & IgM) produced by the body in response to the infection. NS1 and IgM is secreted into the blood during dengue infection and are detectable within 3-4 days of illness.

What is 3rd stage of dengue?

Stage III: This is the recovery phase. It usually takes a few days for the patients to get back to normal. At this stage, the patient gains back its appetite, has a slower pulse rate, has a convalescent rash at legs and arms.

How is NS1 positive treated?

The NS1 antigen test is the most effective for early diagnosis of dengue infection. The main focus of treatment is to ensure that the patient gets adequate hydration. Acetaminophen (paracetamol) is used to manage the fever. If the symptoms are treated properly, the patient should recover in around two weeks.