What does hormone receptor negative mean?

Listen to pronunciation. (HOR-mone reh-SEP-ter NEH-guh-tiv) Describes cells that do not have a group of proteins that bind to a specific hormone. For example, some breast cancer cells do not have receptors for the hormones estrogen or progesterone.

What does progesterone receptor negative mean?

Cancer cells that are progesterone receptor negative do not need progesterone to grow. This means that they will keep growing when progesterone is not present and do not stop growing when treated with substances that block progesterone from binding. Also called PR negative.

What does luteinizing hormone releasing hormone do?

A hormone made by a part of the brain called the hypothalamus. Luteinizing hormone-releasing hormone causes the pituitary gland in the brain to make and secrete the hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In men, these hormones cause the testicles to make testosterone.

What is estrogen receptor negative?

Listen to pronunciation. (ES-truh-jin reh-SEP-ter NEH-guh-tiv) Describes cells that do not have a protein that binds to the hormone estrogen. Cancer cells that are estrogen receptor negative do not need estrogen to grow.

Is it better to be ER-positive or negative?

Tumors that are ER/PR-positive are much more likely to respond to hormone therapy than tumors that are ER/PR-negative. You may have hormone therapy after surgery, chemotherapy, and radiation are finished. These treatments can help prevent a return of the disease by blocking the effects of estrogen.

What does low LH mean?

Low LH levels can signify that your pituitary gland isn’t making the LH needed to spur changes in your body that support sexual development or reproduction. Low LH levels can be a sign of: Kallmann syndrome: A rare condition that leads to insufficient testosterone and estrogen production.