What does reticulin stain for?

Stain of reticulin is a staining that stains the reticulinic fibers of the stroma and makes it possible to specify the architecture of the tumors (as for example the follicular architecture). It is very useful in cases where the tumor is necrotic.

What is the stain of the reticular fibers?

ammoniacal silver solutions
Reticular fibers are highly branched, delicate, argyrophilic fibers that stain with ammoniacal silver solutions.

Is reticulin a silver stain?

Reticulin fibers are agyrophilic, meaning that these tissue elements will stain black with a silver solution using the aid of a chemical reducer, which brings the silver into a visible form. This silver staining process is known as silver impregnation.

What does the reticulin stain highlight in a liver biopsy?

Reticulin Stain By highlighting these fibers, the stain helps in the assessment of the architecture of the hepatic plates, such as expansion in regenerative and neoplastic conditions, compression of plates in nodular regenerative hyperplasia,4 and collapse of the reticulin framework in necrosis (Fig. ​ 2).

What stain is used to stain collagen?

Mason’s Trichrome stain
Mason’s Trichrome stain is used to highlight connective tissue fibers in a tissue section. Collagen fibers are stained a blue hue, nuclei a blue-black, and cytoplasm, keratin, and muscle fibers a range of pink to red hues.

What is the Colour of reticular fibers?

Reticular fibers are usually observed as a delicate meshwork of fine fibrils stained black by the silver impregnation method. They usually underlie the epithelium and cover the surface of such cells of muscle cells, adipose cells and Schwann cells.

What is reticulin fibrosis in bone marrow?

Reticulin is a normal component of the bone marrow stroma and can be detected with a reticulin stain in 73% to 81% of healthy subjects. 16-19. Increased reticulin staining (reticulin fibrosis) is associated with many benign conditions as well as some malignant diseases.