What is dissolution Apparatus 1?

Drug Dissolution Apparatus-I USP (Rotating Basket) The rotating basket apparatus (Apparatus 1) consists of a cylindrical basket held by a motor shaft. The basket holds the sample and rotates in a round flask containing the dissolution medium. The entire flask is immersed in a constant-temperature bath set at 37°C.

What is dissolution S1 S2 S3?

What Are S1 S2 And S3 stages In Dissolution in pharmaceutical? In the pharmaceutical industry, it is a very important test to know the drug dissolution rate in the defined medium. Dissolution is an in-vitro test (Outside body) to predict the invivo (In body) results of the drug.

How many types of DT are there?

Types of Dissolution Apparatus / DT Apparatus According to United States Pharmacopoeia and European Pharmacopoeia, four types of apparatus are used to identify the characteristics of the solid dosage form.

What are the types of dissolution apparatus?

Currently, there are seven different types of dissolution apparatus defined in the United States Pharmacopeia (USP)-basket type, paddle type, reciprocating cylinder, flow through cell, paddle over disc, rotating cylinder, and reciprocating disc.

What is dissolution test apparatus?

A dissolution test uses an apparatus with specific test conditions in combination with acceptance criteria to evaluate the performance of the product. General chapter <711> Dissolution includes 4 standardized apparatus: basket, paddle, reciprocating cylinder, and flow-through cell.

What is F1 and f2 value?

The f1 value is 0 when the test and the reference profiles are identical and increases proportionally with the dissimilarity between the two profiles. The f2 value is between 0 and 100. The value is 100 when the test and the reference profiles are identical and approaches zero as the dissimilarity increases 6, 11, 12.

What are the different types of dissolution apparatus?