What is nasal NK lymphoma?

Extranodal natural killer (NK)/T-cell lymphoma, nasal type, is a rare peripheral T-cell lymphoma associated with Epstein-Barr virus. It most often presents as limited-stage disease in patients of East Asian descent with a palatal deformity caused by erosion of the tumor through the hard palate.

Can you get lymphoma in the nose?

Lymphomas (cancers starting in immune system cells called lymphocytes) can occur in the nasal cavity and paranasal sinuses and are the third most common cancer found in this area. One type of lymphoma seen in this area, T-cell/natural killer cell nasal-type lymphoma, was previously called midline lethal granuloma.

How do you treat nasal NK lymphoma?

Nasal NK/T-cell lymphomas present mostly with stage I/II disease. Concomitant/sequential chemotherapy and radiotherapy is standard treatment. Radiotherapy alone is inadequate because of high systemic failure rate. For stage III/IV nasal, nonnasal, and disseminated lymphomas, systemic chemotherapy is indicated.

Is NK T-cell lymphoma curable?

In the retrospective International Peripheral T-cell Lymphoma Project, the median overall survival among patients with ENKL was 3 years for localized and 8 months for advanced disease. Despite the short median overall survival, with most current treatment approaches, a significant number of patients are cured.

What causes nasal lymphoma?

Extranodal NK/T-cell lymphoma, nasal type, is strongly linked to infection with a virus called Epstein-Barr virus (EBV). EBV is a very common virus that can cause glandular fever. After you’ve been infected with it, EBV stays in your body but it is normally kept under control by your immune system.

Which type of lymphoma is curable?

Hodgkin lymphoma is one of the most curable types of cancer. Treatment options include the following: Chemotherapy. Chemotherapy and radiation that directly targets the lymphoma.

How common is nasal lymphoma?

About nasal and sinus tumors Nasal and sinus tumors are benign or cancerous tumors that occur in the nose or sinuses. Cancerous nasal cavity or sinus tumors are rare, with only about 2,000 being diagnosed in the United States each year.

Does lymphoma cause sinus problems?

The nasal cavities and paranasal sinuses are rarely affected by primary NHL. Common primary extranodal sites of lymphomas include stomach, liver, soft tissue, dura, bone, intestine and bone marrow.

What are the symptoms of NK T-cell lymphoma?

Symptoms. Most people are diagnosed with extranodal NK/T-cell lymphoma, nasal type, at an early stage (stage 1 or 2) when it causes a blockage in the nose. This disease can also cause swelling of the face, discharge from the nose and nosebleeds.