What is the antidote for salicylism?

There is no specific antidote for salicylism. Treatment is currently aimed at augmenting elimination of salicylate via the urine or, in severer cases, directly from the blood by hemodialysis or exchange transfusion. Ninety per cent of ingested salicylate is excreted by the kidney.

What are side effects of salicylism?

(Salicylism) Salicylate poisoning can cause vomiting, tinnitus, confusion, hyperthermia, respiratory alkalosis, metabolic acidosis, and multiple organ failure.

What is the toxicity of aspirin?

A toxic dose of aspirin is 200 to 300 mg/kg (milligrams per kilogram of body weight), and ingestion of 500 mg/kg is potentially lethal. In chronic overdose a lower level of aspirin in the body can result in serious illness. Much lower levels can affect children.

What drug causes salicylate toxicity?

Ingestion of topical products containing salicylates (eg, Ben-Gay, salicylic acid [keratolytic], oil of wintergreen or methyl salicylate), can cause severe salicylate toxicity.

What is the antidote for digoxin?

Digoxin-specific antibody antigen-binding fragments (DSFab), brand name Digibind or Digifab, are an effective antidote that directly binds digoxin. DSFab is indicated for life-threatening toxicity including: Ventricular arrhythmias.

How much methyl salicylate is toxic?

A therapeutic level is approximately 10 to 25 mg/dL. Symptoms of toxicity may appear at levels of 60 to 70mg/dL in chronic exposure. A salicylate level greater than 100mg/dL is typically considered to be severe poisoning. The salicylate level should be followed serially, as the half-life can vary with exposure amounts.

What do you mean by Salicylism?

[ săl′ĭ-sə-lĭz′əm ] n. A toxic syndrome caused by excessive doses of salicylic acid or any of the salicylates. GOOSES.

What causes Salicylism?

Definition: Salicylate toxicity is characterized by a constellation of symptoms caused by acute or chronic overdose of salicylate containing compounds.