What is the difference between collagen and procollagen?

Collagen represents 70% of the dry weight of skin. The fibroblast synthesizes the procollagen molecule, a helical arrangement of specific polypeptide chains that are subsequently secreted by the cell and assembled into collagen fibrils. Collagen is rich in the amino acids hydroxyproline, hydroxylysine, and glycine.

What type of collagen is procollagen?

Type I collagen
1 PROCOLLAGEN PROPEPTIDES Type I collagen is a trimer comprising two identical α1 (I) polypeptide chains and one α2 (I) polypeptide chain and is the major protein of bone matrix (90%) (1).

What does procollagen mean?

Procollagen: A precursor (forerunner) of collagen, the protein that adds strength and support to many body tissues.

What is the function of procollagen?

The procollagen C-propeptides of the fibrillar collagens play key roles in the intracellular assembly of procollagen molecules from their constituent polypeptides chains, and in the extracellular assembly of collagen molecules into fibrils.

What is procollagen peptide?

The amino terminal of type III procollagen peptide (P3NP) is an extension peptide that is cleaved and liberated into extracellular fluid and is a serum marker of collagen turnover. Increased levels occur as a consequence of tissue repair and fibrosis that can be used to predict liver damage.

What is the difference between procollagen and Tropocollagen?

The procollagen molecules are then transferred to the outside of the fibroblast through the process of exocytosis. As they leave the cell, some amino acids are cleaved from the ends of the procollagen molecules, resulting in a remodeled protein called tropocollagen.

Which type of collagen is best?

Type I collagen is usually considered best for the skin. It is the most abundant type of collagen in the body. It maintains healthy bones, skin, hair and nails. Like all types of collagen, levels of type I collagen begin to decline after about 25 years of age.

What form of collagen is best?

Collagen peptides are usually considered the best form of collagen for ingestion. Hydrolyzed collagen should be taken if a person wants to take a collagen supplement. Hydrolyzed collagen means the collagen has been broken down into small peptides, which are easy for the body to digest.