What is the drug Spiromide used for?

Spiromide Tablet is a combination of two medicines used to reduce excess fluid levels in the body while maintaining the potassium balance. It is used to treat edema (fluid overload) and some cases of hypertension.

What are the side effects of Spiromide?

Major & minor side effects for Spiromide (50/20 mg) Tablet

  • Low magnesium levels.
  • Decreased calcium level.
  • Hearing impairment.
  • Headache.
  • Weakness.
  • Increased sensitivity of the skin to sunlight.
  • Muscle spasm.
  • Skin rash.

What class of drug is spironolactone?

Spironolactone is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body.

What drugs should not be taken with spironolactone?

Taking certain medications with spironolactone can increase the amount of potassium in your body to unsafe levels. Examples of these drugs include: angiotensin-converting enzyme (ACE) inhibitors, such as: benazepril….angiotensin II receptor blockers (ARBs), such as:

  • irbesartan.
  • losartan.
  • olmesartan.
  • telmisartan.
  • valsartan.

What causes diuretic resistance?

The causes of diuretic resistance include poor adherence to drug therapy or dietary sodium restriction, pharmacokinetic issues, and compensatory increases in sodium reabsorption in nephron sites that are not blocked by the diuretic.

Why spironolactone and furosemide are prescribed together?

When you take FUROSEMIDE+SPIRONOLACTONE,. It helps in losing out excess fluids from the body by increasing the production of urine. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body.

Is Spiromide a diuretic?

Spiromide Tablet is a fixed-dose combination of furosemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics and they help to remove excess fluid from the body.

How long does it take for spironolactone to get out of your system?

Spironolactone has a relatively short half-life of approximately 1.4 hours, meaning a standard dosage will exit your system relatively quickly. However, some metabolites of spironolactone have a significantly longer half-life and may stay in your body for several days before being fully eliminated.

Why is spironolactone a hazardous drug?

2.3 Harmful if inhaled, swallowed, or in contact with skin. Material may be irritating to the mucous membranes and upper respiratory tract. May cause eye, skin, or respiratory system irritation. Suspected of causing cancer.

How long does it take to get spironolactone out of your system?

Do diuretics cause kidney damage?

Diuretics, or water pills, are used to treat conditions like high blood pressure, glaucoma, and edema, but as with all medications, they come with some risks. Popular diuretics include hydrochlorothiazide, furosemide, and spironolactone. They are associated with a risk for acute kidney injury.

Is spironolactone a strong diuretic?

Aldactone (spironolactone) should be used with other medicines to get rid of excess fluid in your body, especially if you have heart failure. A strong diuretic (water pill) that works well to get rid of extra fluids in your body through urination.

Does spironolactone make you pee more?

SPIRONOLACTONE (speer on oh LAK tone) is a diuretic. It helps you make more urine and to lose excess water from your body. This medicine is used to treat high blood pressure, and edema or swelling from heart, kidney, or liver disease.

What is bisoprolol Unicorn 5 used for?

Bisoprolol is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

How long does 50mg of spironolactone stay in your system?

How long does spironolactone stay in your system? Spironolactone has a half-life of approximately 90 minutes. While this is relatively short, the metabolites, substances derived from spironolactone, have longer half-lives ranging from three to more than 11 hours.

How quickly does spironolactone lower testosterone?

Interestingly, administration of the main metabolite of spironolactone, canrenone, appears to decrease testosterone by 50–60% within hours in healthy men (13) and in conjunction with oestradiol, spironolactone decreases testosterone (14).

Does spironolactone cause feminization?

Because of its antiandrogenic activity, spironolactone can, in men, cause breast tenderness, gynecomastia (breast development), feminization in general, and demasculinization, as well as sexual dysfunction including loss of libido and erectile dysfunction, although these side effects are usually confined to high doses …

Does spironolactone make you look more feminine?

Feminizing hormone therapy often involves taking estrogen and anti-androgen hormones, such as estradiol or spironolactone. By taking these hormones, you may be able to achieve more traditionally feminine characteristics, including breast growth, body fat redistribution, and less facial hair.