What is the function of the cytochrome c protein?
What is the function of the cytochrome c protein?
Cytochrome c is functionally involved in the electron transport chain of mitochondria. That electron transport is part of the pathway for synthesis of ATP. The role of cytochrome c is to carry electrons from one complex of integral membrane proteins of the inner mitochondrial membrane to another (Fig. 10.3).
What is the function of the proteins cytochrome c and hemoglobin?
Cytochrome c is a small globular protein containing iron porphyrin cofactor (heme c) that is covalently bound to the only polypeptide chain. The main function of cytochrome c is its involvement in the electron transport chain of the mitochondrial inner membrane. It is a key element that ensures cellular respiration.
What function does cytochrome c oxidase perform Why is this function important?
Cytochrome oxidase is a widespread respiratory enzyme that conserves energy released when oxygen is reduced by pumping protons across the membrane in which it is located.
What is the role of cytochrome c in metabolism?
Cytochrome c oxidase is the terminal complex of eukaryotic oxidative phosphorylation in mitochondria. This process couples the reduction of electron carriers during metabolism to the reduction of molecular oxygen to water and translocation of protons from the internal mitochondrial matrix to the inter-membrane space.
What is the role of cytochrome c in apoptosis?
During cell apoptosis cytochrome c is released into the cytoplasm where it binds and activates the apoptotic protease activating factor-1 (Apaf-1) allowing its binding to ATP and the formation of the ring-like apoptosome.
What role does cytochrome c play in the electron transport chain?
Cytochrome c is a component of the respiratory electron transport chain in mitochondria. The heme group of cytochrome c accepts electrons from the bc1 Complex III and transports them to Complex IV, while it transfers energy (derived from O2) in the opposite direction.
What is the evolutionary significance of the protein cytochrome c?
Cytochrome c is primarily known as an electron-carrying mitochondrial protein. The transition of cytochrome c between the ferrous and ferric states within the cell, makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals.
Is cytochrome c oxidase A protein?
Cytochrome c oxidase (CcO) is a large integral membrane protein which is encoded in the mitochondrial genome. It is a terminal oxidase of the mitochondrial electron transport chain, and it is expressed in the mitochondrial inner membrane.
How does cytochrome c activate caspases?
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition | Cell Death & Disease.