What is the histology of the proximal convoluted tubule?

The proximal convoluted tubule is lined by a simple cuboidal epithelium whose cells have several characteristic features, each of which affects the appearance of the tubule. The apical end of each proximal tubule cell has a brush border of microvilli.

Which epithelium is found in PCT of nephron?

simple cuboidal epithelium
The proximal convoluted tubule is lined by a simple cuboidal epithelium with a brush border of microvilli, which greatly increase the surface area of the inner lining of the tubule in order to maximize the number of active and passive transport proteins in the lining cell membranes.

What is absorbed in the late proximal tubule?

Cl− is absorbed passively in later proximal tubule by both a chemical gradient and a transluminal electrical gradient. The proximal tubule normally reabsorbs 100% of filtered glucose, amino acids, and small peptides. On the apical surface, this movement is due to Na+-coupled cotransport.

What type of cells line the PCT?

Epithelial cells in the proximal convoluted tubule (PCT) reabsorb components of the glomerular filtrate that have nutritional significance (e.g., glucose, ions and amino acids). To facilitate absorption, these cells have numerous microvilli, Mv, along their apical surface.

Which type of tissue is found in PCT and collecting duct?

First, the proximal convoluted tubule – which is the longest part of the renal tubule – has a simple tall cuboidal epithelium, with a brush border (microvilli). The epithelium almost fills the lumen, and the microvilli increases the surface area by 30-40 fold.

What is the main difference between PCT and DCT?

Proximal Convoluted Tubule (PCT) receives primary urine from glomerulus. Distal Convoluted Tubule (DCT) receives urine from the glomerulus. PCT regulates excretion of urine by absorbing excess water from primary urine. In DCT, water and salts are secreted.

How do you identify distal convoluted tubules histology?

In contrast to the proximal tubules, epithelial cells of the distal convoluted tubules (DCT) lack apical microvilli, and therefore, using a periodic acid-Schiff (PAS stain), the DCT can be identified by their lack of pink brush border staining (red arrow).

Which type of tissue is found in PCT and DCT?

So, the correct option is ‘Cuboidal epithelium with brush border’.

Which cells are present in PCT?

What is the function of PCT?

PCT is the region of renal tubule where reabsorption of essential substances like glucose, proteins, amino acids, a major portion of electrolytes and water takes place. The surface area for reabsorption is facilitated by the lining of the simple cuboidal epithelium in them.

What substances are secreted in the proximal tubules?

The proximal tubule efficiently regulates the pH of the filtrate by exchanging hydrogen ions in the interstitium for bicarbonate ions in the filtrate; it is also responsible for secreting organic acids, such as creatinine and other bases, into the filtrate.