What undesirable side effects should the nurse watch for with a neuromuscular blocking agent?

Adverse Effects

  • Profound and prolonged muscle paralysis.
  • Respiratory paralysis characterized by depressed respiration, bronchospasm, and apnea.
  • Prolonged drug use: GI paralysis, constipation, vomiting, regurgitation, aspiration.

Is it always necessary to reverse the neuromuscular blockade at the end of surgery?

In summary, a neuromuscular block should always be fully reversed if it is still present at the end of surgery.

What are the results of neuromuscular blocking agents blocking the effects of acetylcholine?

Nondepolarizing neuromuscular blockers are competitive acetylcholine (ACh) antagonists that bind directly to nicotinic receptors on the postsynaptic membrane, thus blocking the binding of ACh so the motor endplate cannot depolarize. [4] This leads to muscle paralysis.

What are the side effects of succinylcholine?

Common side effects of succinylcholine include:

  • Jaw rigidity.
  • Low blood pressure (hypotension)
  • Muscle fasciculation may result in postoperative pain.
  • Muscle relaxation resulting in respiratory depression to the point of breathing cessation (apnea)
  • Respiratory depression.
  • Salivary gland enlargement.

Can succinylcholine be reversed?

Oxygen saturation can fall to critically low levels leading to cerebral and cardiac anoxia Faced with a CVCI (cannot intubate ,cannot ventilate) situation, reversal of succinylcholine induced paralysis can be life saving .

Which adverse effects would a nurse most likely assess in a client who is receiving a centrally acting skeletal muscle relaxant?

Use of centrally acting muscle relaxants may result to these adverse effects: CNS: depression, drowsiness, fatigue, weakness, confusion, headache, insomnia. CV: hypotension, arrhythmias.

What are the side effects of rocuronium?

Common side effects of Zemuron include:

  • nausea,
  • vomiting,
  • swelling or discomfort at the injection site,
  • sleepiness or lightheadedness,
  • mild itching or skin rash, or.
  • high or low blood pressure (hypertension or hypotension).

When is neuromuscular blockade reversal used?

An ideal reversal agent could be given at any time after the administration of a neuromuscular blocking agent (NMBA), and should have no muscarinic side-effects.

How do you reverse neuromuscular blockade?

AGENTS REVERSING NEUROMUSCULAR BLOCKADE [2] NMBAs may be reversed either by increasing the concentration of acetylcholine in the synaptic junction or aid the elimination of the drug or its metabolism.

Which is an important action of neuromuscular blocking agents?

Neuromuscular blocking agents (NMBAs) are used to facilitate endotracheal intubation and provide skeletal muscle relaxation during surgery or mechanical ventilation.

What happens if you give too much succinylcholine?

Administered doses of succinylcholine higher than those recommended based on the patient’s actual body weight may result in neuromuscular blockade toxicity, potentially resulting in neuromuscular paralysis beyond the time required for procedures, surgical interventions, and anesthesia.