Which chemotherapy agent has the lowest emetogenic potential?

Drugs considered to have low emetogenic risk (10%-30%) include the taxanes, etoposide, and biologics such as trastuzumab (Herceptin) and cetuximab (Erbitux).

Which oral chemotherapy has the highest emetogenic potential?

Emetogenic potential of oral antineoplastic agents most used in solid tumors (based on MASCC and ESMO guidelines 2010)….Table 1.

MASCC and ESMO guidelines 2010
Degree of emetogenicity (incidence) Agent
High (>90%) Procarbazine
Moderate (30–90%) Cyclophosphamide

What is emetogenic potential?

GLOSSARY. Emetogenicity: the propensity of an agent to cause nausea, vomiting or retching. High emetic potential: greater than 90% frequency of emesis in the absence of effective prophylaxis.

Is carboplatin highly emetogenic?

The NCCN has recently reclassified carboplatin emetogenicity according to the AUC (target area under the concentration versus time curve) with a carboplatin AUC ≥4 classified as highly emetogenic and carboplatin AUC < 4 as moderately emetogenic – but highly emetogenic in certain patients.

How long does Emend stay in your system?

Emend can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication.

How much does Emend cost?

The cost for Emend oral capsule 80 mg is around $470 for a supply of 2 capsules, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Emend is available, see aprepitant prices.

How frequently can you give Emend?

Administer EMEND for injection on Day 1 as an intravenous infusion over 20 to 30 minutes (adults), 30 minutes (12 years to 17 years) or 60 minutes (6 months to less than 12 years) completing the infusion approximately 30 minutes prior to chemotherapy.